Database : HANSEN Search on : SARCOMA DE KAPOSI/DIAG [Subject descriptor] References found : 2 [refine] Displaying: 1 .. 2   in format [Detailed]

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Id: 17964 Author: Gloster HM; Neal K Title: Skin cancer in skin of color Skin cancer in skin of color-v.55 Source: s.l; s.n; 2006. 19 p. ilus, tab. Abstract: Skin cancer is less common in persons with skin of color than in light-skinned Caucasians but is often associated with greater morbidity and mortality. Thus, it is crucial that physicians become familiar with skin cancer in persons of color so as to maximize the likelihood of early detection of these tumors. In dark-skinned ethnic groups, squamous cell carcinoma is most common; squamous cell carcinoma and melanoma usually occur on nonsun-exposed sites; and ultraviolet radiation is not an important etiologic factor for skin cancer with the exception of basal cell carcinoma. Races of intermediate pigmentation, such as Hispanics and Asians, share epidemiologic and clinical features of dark-skinned ethnic groups and Caucasians. Skin cancers pose a significant risk in skin of color and clinicians should focus on preventive measures in these groups such as regular skin exams, self-examination, public education, and screening programs. LEARNING OBJECTIVE: At the completion of this learning activity, participants should be familiar with the epidemiology and unique clinical features of skin cancer in skin of color and be aware of strategies to prevent skin cancer in skin of color.(AU). Descriptors: NEOPLASIAS CUTÂNEAS/quim NEOPLASIAS CUTÂNEAS/compl NEOPLASIAS CUTÂNEAS/diag NEOPLASIAS CUTÂNEAS/genet NEOPLASIAS CUTÂNEAS/imunol NEOPLASIAS CUTÂNEAS/prev NEOPLASIAS CUTÂNEAS/fisiopatol NEOPLASIAS CUTÂNEAS/reabil NEOPLASIAS CUTÂNEAS/radioter NEOPLASIAS CUTÂNEAS/cirurg NEOPLASIAS CUTÂNEAS/terap SARCOMA DE KAPOSI/compl SARCOMA DE KAPOSI/diag SARCOMA DE KAPOSI/fisiopatol - RAIOS ULTRAVIOLETA/uso diag  TERAPIA ULTRAVIOLETA/instrum  TERAPIA ULTRAVIOLETA/métodos Limits: ESTUDO COMPARATIVO HUMANO Location: BR191.1; 00326/cme

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Id: 12316 Author: Geraminejad, Pedram; Memar, Omeed; Aronson, Iris; Rady, Peter L; Hengge, Ulrich; Tyring, Stephen K Title: Kaposi's sarcoma and other manifestations of human herpesvirus 8 ..- Source: s.l; s.n; Nov. 2002. 15 p. ilus, tab. Abstract: Kaposi's sarcoma (KS) was described by Moritz Kaposi in 1872 and was known for an entire century as a rare disorder of older men usually of Eastern European, Mediterranean, and/or Jewish origin. In the early 1980s, the prevalence of KS began to increase dramatically and soon became the most common malignancy in patients with AIDS, especially those who were male homosexuals. In 1994, a new human herpesvirus (HHV) was found to be present in almost 100% of KS lesions. This virus was found to be a gammaherpesvirus, closely related to Epstein-Barr virus, and was designated HHV-8. Subsequently, HHV-8 DNA was found in almost all specimens of classic KS, endemic KS, and iatrogenic KS, as well as epidemic KS (ie, AIDS KS). It is now believed that HHV-8 is necessary, but not sufficient, to cause KS and that other factors such as immunosuppression play a major role. The use of highly active antiretroviral therapy (HAART) since 1996 has markedly reduced the prevalence of AIDS KS in western countries, but because 99% of the 40 million patients with AIDS in the world cannot afford HAART, KS is still a very common problem. Primary effusion lymphoma and multicentric Castleman's disease are also thought to be due to HHV-8. Although HHV-8 DNA has been described in a number of other cutaneous disorders, there is little evidence that HHV-8 is of etiologic significance in these diseases. The mechanism by which HHV-8 causes KS, primary effusion lymphoma, and multicentric Castleman's disease is not well understood but is thought to involve a number of molecular events, the study of which should further our understanding of viral oncology. (J Am Acad Dermatol 2002;47:641-55.) Learning objective: At the completion of this learning activity, participants should be familiar with Kaposi's sarcoma and other manifestations of human herpesvirus 8.. Descriptors: PRODUTOS DO GENE TAT INFECÇOES POR HERPESVIRIDAE HIPERPLASIA DO LINFONODO GIGANTE INTERLEUCINA-6 LINFOMA DE CÉLULA-B LINFOMA DE CÉLULA-B SARCOMA DE KAPOSI SARCOMA DE KAPOSI SARCOMA DE KAPOSI SARCOMA DE KAPOSI TERAPIA ANTI-RETROVIRAL DE ALTA ATIVIDADE FASES DE LEITURA ABERTA/fisiologia HERPESVIRUS 8 HUMANO/fisiologia ESTUDOS SOROEPIDEMIOLOGICOS Limits: HUMANO Location: BR191.1; 0274/cme

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